Kimberlee Mix joined the Department of Biological Sciences in the fall of 2009. Dr. Mix's research is focused on inflammatory joint diseases such as rheumatoid arthritis and osteoarthritis. The goal of her research is to understand the molecular and cellular events that contribute to cartilage and bone damage during disease progression. Molecular studies are aimed at identifying novel therapeutic targets that regulate the structure and function of joints. Dr. Mix and her research students are investigating roles of the NR4A orphan nuclear receptors in cartilage and synovial tissues. As transcription factors, these receptors regulate subsets of genes involved in the degradation of cartilage and the proliferation of cells. Current projects involve monitoring expression patterns of the NR4A receptors in models of inflammatory arthritis and identifying disease-specific transcriptional targets. Students interested in participating in these research projects and gaining hands-on experience in the laboratory are encouraged to contact Dr. Mix.
Ph.D., Dartmouth College, 2003; B.S., Worcester Polytechnic Institute, 1998
- Cells & Heredity
- Molecular Genetics
Areas of Expertise
Biochemistry, Immunology, Cell and Molecular Biology